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Editor's Correspondence | September 25, 2000

Antipyretic Therapy Is Important Following Stroke

Andrew McD Johnston, MRCP

Arch Intern Med. 2000;160(17):2679-2680. doi:.

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In their review of antipyretic therapy Plaisance and Mackowiak¹ fail to mention the role of such therapy in acute ischemic stroke. It is well recognized that the occurrence of fever is a poor prognostic indicator following stroke,²^- 4 and is related to the size of the infarcted area.⁵ There is evidence that treating fever by inducing hypothermia reduces the degree of damage in animal models⁶ and improves outcomes markedly in humans.⁷ Experts in stroke treatment now recommend treating raised temperature with antipyretics.⁸^- 9 We believe that the authors should have mentioned the role of antipyretic therapy in stroke.

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McD Johnston A. Antipyretic Therapy Is Important Following Stroke. Arch Intern Med. 2000;160(17):2679-2680. doi:.

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