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Editor's Correspondence |

Valacyclovir Hydrochloride Therapy and Thrombotic Thrombocytopenic Purpura in a HIV-Infected Patient

Elisabeth Rivaud, MD; Marie-Ange Massiani, MD; François Vincent, MD; Elie Azoulay, MD; Louis-Jean Couderc, MD
Arch Intern Med. 2000;160(11):1705-1706. doi:.
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Cases of thrombotic thrombocytopenic purpura (TTP) have been reported in patients who are infected with the human immunodeficiency virus (HIV).1,2 Recently, manifestations resembling TTP have been reported in HIV-infected patients who were treated with high-dose valacyclovir hydrochloride, 8 g/d.3 We report here a case of TTP in an HIV-infected patient who was treated with a lower dose of valacyclovir.

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