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Editor's Correspondence | May 22, 2000

Thyroid Nodules and Carcinoma in Graves Disease

Jan Čáp, MD, PhD; Aleš Ryška, MD

Arch Intern Med. 2000;160(10):1537-1538. doi:.

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The article by Cantalamessa and colleagues¹ points out that thyroid nodules occur with a high frequency in patients with Graves disease as determined by ultrasonography and pathological examination findings. Nevertheless, the authors discovered only 1 case of carcinoma among 315 consecutive patients (0.3%), including 106 with nodules. Surprisingly, this is a rather low frequency compared with previous studies and the findings from a recent series.² We assume that this low frequency is the result of the fact that only 20 patients underwent surgery.

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Čáp J, Ryška A. Thyroid Nodules and Carcinoma in Graves Disease. Arch Intern Med. 2000;160(10):1537-1538. doi:.

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