Periodontitis is the leading cause of tooth loss and affects nearly 40% of the US adult population.1 The American Dental Association has estimated that in 1999 more than 28 million periodontal procedures were performed in the United States alone.2 These treatments result in significant transient bacteremias and periodontal tissue damage. We recently reported that scaling and root planing, the most frequently performed procedure, result in a significant systemic inflammatory response of 1 week’s duration.3 We report herein the magnitude of changes in serum levels of a cluster of traditional and novel markers of cardiovascular risk after periodontal therapy.
. Acute changes in inflammatory and lipid markers. Line plots of changes in serum concentrations of C-reactive protein (A), total (TC) and high-density lipoprotein cholesterol (HDL-C) (B), and neutrophils and lymphocytes (C). Values are given as means and 95% confidence Intervals. To convert cholesterol to milligrams per deciliter, divide by 0.0259.
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