0
Editor's Correspondence |

Use of PPIs Are Not Associated With Mortality in Institutionalized Older People—Reply

J. Simon Bell, PhD; Timo E. Strandberg, MD, PhD; Kaisu H. Pitkälä, MD, PhD
Arch Intern Med. 2011;171(9):866-867. doi:10.1001/archinternmed.2011.165.
Text Size: A A A
Published online

Extract

In reply

We thank Wilson and colleagues for sharing their finding that baseline use of PPIs was not associated with 12-month mortality among 602 participants in a falls prevention study. As highlighted by Wilson and colleagues, prescribing practices and organization of care for older people often differ within and between countries. We agree that the specialized nature of our study cohorts limits extrapolation to other populations.

Twelve-month mortality among the residents of intermediate-level aged care facilities studied by Wilson and colleagues was 10.3% compared with 28.2% and 24.9% in our 2 cohorts.1 In addition to possible differences in organization of care, the lower mortality may attributed to the fact that residents were only eligible for inclusion in their falls prevention study if facility staff judged that they were likely to survive for 12 months.2 It is possible, therefore, that frail residents most susceptible to adverse drug events associated with PPIs were not included in the study.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

May 9, 2011
J. Simon Bell, PhD; Timo E. Strandberg, MD, PhD; Kaisu H. Pitkälä, MD, PhD
Arch Intern Med. 2011;171(9):866-867. doi:10.1001/archinternmed.2011.165.
CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Topics
PubMed Articles
Jobs
JAMAevidence.com


Mortality

brightcove.createExperiences();