Details of physical activity were available for 782 clinically healthy men with various cardiovascular risk factors. Men answering yes to question 1 were categorized as low activity (n = 148); yes to question 2, as moderate activity (n = 398); and yes to questions 3 and 4, as high activity (n = 236 [among whom only 11 men had a competitive activity level). After a 26-year follow-up in 2000 (median age, 73 years; range, 66-81 years), 552 men (91% of survivors at that time [deaths were verified from the Central Population Register]) could be reassessed using a mailed questionnaire. The questionnaire included queries about anthropometric measures, housing, prevalence of chronic diseases, medication, and lifestyle factors. The Finnish version of the RAND-36 Item Health Survey 1.0, which is practically the same as SF-36 and validated in the Finnish population,3 was embedded into the questionnaire. From the responses, a summary comorbidity index was also assessed according to the method of Charlson et al.4 The 8 domains of RAND-36 were physical function, role physical, bodily pain, general health, vitality, social function, role emotional, and mental health. Analyses were performed using NCSS 2004 statistical software (NCSS, Kaysville, Utah). Analysis of covariance was used to compare baseline activity groups, and P < .05 was considered statistically significant.