Dramatic increases in the use of herbal and other natural products were reported during the last decade. Data obtained from a nationwide random digit dialing survey were examined to determine which dietary supplements American adults use, whether the prevalence has continued to increase in recent years, and whether the popularity of individual supplements has changed. The weekly prevalence of dietary supplement use increased from 14% in 1998-1999 to 19% in 2002. However, the increase was entirely accounted for by the use of lutein, a new addition to multivitamin products; the overall 2002 prevalence excluding lutein was 14%. Thus, although the sharp increase in supplement use in the 1990s appears to have slowed, the addition of supplements such as lutein and lycopene to mainstream multivitamins has become an important source of exposure.