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Editor's Correspondence |

Clinical Trials of Antioxidant Supplementation in the Prevention of Cardiovascular Events—Reply

Nancy R. Cook, ScD; Christine M. Albert, MD, MPH; JoAnn E. Manson, MD, DrPH; WACS Investigator Group
Arch Intern Med. 2008;168(7):773-774. doi:10.1001/archinte.168.7.773-b.
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We thank Katsiki and Manes for their interest in our study,1 which addresses the role of antioxidant vitamins, alone and in combination, in the prevention of cardiovascular events. Although our trial included only women, several antioxidant trials have been conducted in men or women separately, with similar results.2

We note that we provided information about the menopausal status of the study population in our article; this information is presented in Table 1, with subgroup effects by menopausal status given in Table 3.1

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