Editor's Correspondence |

Are We Ignoring the Elephant in the Room?

Ayad Jindeel, MD
Arch Intern Med. 2007;167(20):2263-2264. doi:10.1001/archinte.167.20.2263.
Text Size: A A A
Published online


Cook et al1 reported no association between migraine and coronary heart disease (CHD) after a mean of 12 years of follow-up in the Physicians' Health Study (PHS). This study included information through March 2000. Kurth et al2 extended the follow-up period of the PHS participants to February 2005. They concluded that “migraine was associated with increased risk of major CVD [cardiovascular disease]”2(p795) and that “[t]he associations between migraine and major CVD, ischemic stroke, and MI [myocardial infarction] were not significantly modified by smoking and hypertension status or by randomized aspirin assignment.”2(p797) The authors “had no information about the use of migraine-specific drugs (ie, triptans and ergot alkaloids).”2(p800) However, in a study by the same authors regarding the Women Health Study “women were asked on the 48-month questionnaire to provide information regarding medication use during the previous 2 weeks. The frequency of migraine-specific drug use among women who reported active migraine at baseline was 5.3%.”3(p290) So what did these patients use to treat their migraine?



Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles