The men were divided into 3 groups on the basis of the tertile distribution of adiponectin levels in all men. Thus, similar cutoff points were used for the adiponectin groups in men without diagnosed CVD or heart failure, in those with CVD (no heart failure), and in those with heart failure. Kaplan-Meier curves were used to construct cumulative mortality curves across the 3 adiponectin groups. We used the Cox proportional hazards model to assess the multivariate-adjusted relative risk (RR) for the adiponectin groups. In the adjustment, factors known to be associated with mortality were included. In the multivariate analysis, smoking (never, long-term ex-smokers [>15 years], recent ex-smokers [<15 years], and current smokers), social class (manual vs nonmanual work), physical activity (none/occasional, light, moderate, and moderately vigorous/vigorous),24 alcohol intake (none/occasional, light, moderate, and heavy),24 BMI (<18.5, 18.5-24.9, 25.0-30.0, and ≥30.0), eGFR (<60, 60-69, and ≥70 mL/min/1.73 m2), diabetes mellitus (yes or no), treatment of hypertension (yes or no), use of statins (yes or no), use of β-blockers (yes or no), and weight loss during the preceding 3 years (yes or no) were fitted as categorical variables. Forced expiratory volume in 1 second, homeostasis model assessment product, and levels of C-reactive protein, albumin, and high-density lipoprotein cholesterol were fitted as continuous variables. Tests for trend were performed fitting adiponectin level in its original continuous form. In Table 1 and Table 2, tests for trends were performed across the groups.