0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editor's Correspondence |

Observations From a Statin Myopathy Clinic

Paul S. Phillips, MD; Richard H. Haas, MD
Arch Intern Med. 2006;166(11):1232-1233. doi:10.1001/archinte.166.11.1232-b.
Text Size: A A A
Published online

Extract

We read with great interest the article by Hansen et al,1 which, to our knowledge, is the first published attempt to assess the recovery from a variety of statin-associated muscle disorders. We would like to add to their report observations from a statin myopathy clinic that currently follows over 200 patients with these disorders.

The article's primary finding, that this heterogeneous group of patients ex perienced full resolution of their pain on cessation of statin therapy, conflicts with our observations.2,3 Hansen et al1 grouped patients with a number of statin-induced muscle disorders together. In our subjects, underlying metabolic muscle disorders and the persistence of weakness is greater in patients with statin-associated rhabdomyolysis than in patients with normal creatine kinase myopathy.4 Patients often experience myalgias and demonstrate abnormalities in cardiopulmonary exercise for years after myositis, while complete resolution of myalgias is typical in patients without elevated creatine kinase levels.3 Furthermore, while muscle biopsy results in patients with normal creatine kinase myopathy may improve after the myalgias resolve, the tissue often remains myopathic.5

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles
[In Process Citation]. MMW Fortschr Med 2013;155(19):30.
Jobs
JAMAevidence.com

Users' Guides to the Medical Literature
Clinical Scenario

Users' Guides to the Medical Literature
Statin Dosing and LDL Levels

brightcove.createExperiences();