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Comment & Response |

Uncontrolled Hypertension and Risk of Cardiovascular Mortality in China—Reply

Sarah Lewington, DPhil1; Ben Lacey, FFPH1; Robert Clarke, FRCP1
[+] Author Affiliations
1Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England
JAMA Intern Med. 2016;176(8):1234. doi:10.1001/jamainternmed.2016.3825.
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In Reply We appreciate the interest in our work from Zhou and colleagues. The China Kadoorie Biobank is a large population-based prospective cohort study of 0.5 million adults ages 35 to 74 years (when recruited during 2004-2008) from 10 diverse regions of China.1 We reported that about one-third of the participants had hypertension at recruitment, but less than 5% of these hypertensives had their blood pressure properly controlled (<140 mm Hg systolic and <90 mm Hg diastolic blood pressure).1 We estimated that if these findings were broadly representative, then approximately 750 000 cardiovascular deaths could be attributed to uncontrolled hypertension in China in 2010.


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August 1, 2016
Donghao Zhou, MD; Shiming Wang, MD; Tao Tian, MD
1Department of Geriatric Cardiology, Linyi People’s Hospital, Linyi, China
JAMA Intern Med. 2016;176(8):1233-1234. doi:10.1001/jamainternmed.2016.3819.
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