Published Online: February 22, 2016. doi:10.1001/jamainternmed.2016.0003.
Study concept and design: All authors.
Acquisition, analysis, or interpretation of data: Ayers, Althouse, Dredze, Leas.
Drafting of the manuscript: All authors.
Critical revision of the manuscript for important intellectual content: All authors.
Conflict of Interest Disclosures: Drs Ayers and Althouse reported sharing an equity stake in Directing Medicine LLC, which advises how to implement some of the methods embodied in this work. Dr Dredze reported receiving consulting fees from Directing Medicine LLC and Sickweather LLC, who use social media for public health surveillance. The methods described in this article are not proprietary. No other disclosures were reported.
Additional Contributions: Kurt Ribisl, PhD, and Diana Francis, BA, University of North Carolina, provided feedback but were not compensated for their contribution.