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Comment & Response |

Measurement Methodology: What Does Blood Pressure Mean in the PARTAGE Study?—Reply

Athanase Benetos, MD, PhD1,2,3; Patrick Rossignol, MD, PhD2,3
[+] Author Affiliations
1Department of Geriatrics, University Hospital of Nancy, Nancy, France
2Inserm, U1116, Université de Lorraine, Nancy, France
3Inserm Clinical Investigation Centre, CIC-P 1433, Université de Lorraine, and CHU de Nancy, France
JAMA Intern Med. 2015;175(11):1860. doi:10.1001/jamainternmed.2015.4630.
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In Reply We would like to thank Stergiou et al for their interest in our article.

The PARTAGE study is a pragmatic analysis of how we assess cardiovascular risk in elderly individuals living in nursing homes, a dramatically growing population in all developed societies. We note that antihypertensive treatment is based on blood pressure (BP) measured by the personal physician in the nursing home. In addition to this standard clinical measurement, we proposed assisted self-measurements by applying the precise protocol of the French Society of Hypertension (3 measurements in the morning and 3 measurements in the evening over the course of 3 days, totaling 18 measurements). Following this procedure, we made 2 key observations: (1) BP values recorded with standard clinical procedures were very similar to those obtained with multiple 3-day morning and evening measurements,1 and (2) when using one or the other BP-measurement method, subjects with low systolic BP (<130 mm Hg) receiving combination antihypertensive therapy displayed a statistically significant and clinically relevant 80% higher mortality compared with all other groups of individuals.2


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November 1, 2015
George S. Stergiou, MD, FRCP; Nadia Boubouchairopoulou, MSc; Anastasios Kollias, MD, PhD
1Hypertension Center STRIDE-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece
JAMA Intern Med. 2015;175(11):1859-1860. doi:10.1001/jamainternmed.2015.4627.
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