0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Misinterpretation of the Comparative Safety of Testosterone Dosage Forms

C. Mary Schooling, PhD1
[+] Author Affiliations
1City University of New York School of Public Health and Hunter College, New York
JAMA Intern Med. 2015;175(11):1874-1875. doi:10.1001/jamainternmed.2015.5804.
Text Size: A A A
Published online

Extract

To the Editor Given recent warnings by the US Food and Drug Administration and Health Canada about the potential cardiovascular risk of testosterone administration, the effects of testosterone are of intense interest. Layton et al1 add to the ongoing conversation by using medical records to show higher rates of cardiovascular events in men using testosterone injections than in men using testosterone gels. Understandably, given the difficulties of comparing testosterone users with nonusers in an observational study exploiting administrative data, Layton et al have not yet provided the other key comparison listed in the abstract of the National Institutes of Health grant that funded their work, and that is “to compare rates of cardiovascular events in testosterone users to those of non-users with comparable testosterone levels.”2 Without this key comparison, the findings by Layton et al are difficult to interpret, because neither the cardiovascular risk nor the benefit of testosterone use is given for any dosage form.

Topics

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

November 1, 2015
J. Bradley Layton, PhD; Til Stürmer, MD, MPH, PhD; M. Alan Brookhart, PhD
1Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill
JAMA Intern Med. 2015;175(11):1875-1876. doi:10.1001/jamainternmed.2015.5807.
CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

189 Views
0 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Jobs
brightcove.createExperiences();