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Comment & Response |

Another Report of Familial Spontaneous Coronary Artery Dissection

Anthony J. White, MBBS, PhD1,2; Yuvaraj Malaiapan, MBBS2; Ian T. Meredith, MBBS, PhD2
[+] Author Affiliations
1School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia
2Monash Heart, Monash Health, Melbourne, Australia
JAMA Intern Med. 2015;175(10):1721. doi:10.1001/jamainternmed.2015.3824.
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To the Editor We read with great interest the case series describing occurrence of spontaneous coronary artery dissection (SCAD) in pairs of related individuals from 5 families.1 Familial clustering of such a rare clinical event implies the possibility of genetically determined susceptibility factors in the pathogenesis of SCAD.

We too noticed the phenomenon of a pair of SCAD cases in a mother and daughter treated at our institution.


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October 1, 2015
Kashish Goel, MBBS; Marysia S. Tweet, MD; Sharonne N. Hayes, MD
1Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
JAMA Intern Med. 2015;175(10):1721-1722. doi:10.1001/jamainternmed.2015.3830.
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