We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Study Design for Vitamin D Randomized Clinical Trials

Richard L. Prince, MBChB, BSC, MD, FRACP1; Joshua Lewis, PhD1,2; Peter R. Ebeling, MBBS, MD, FRACP3
[+] Author Affiliations
1School of Medicine and Pharmacology, The University of Western Australia, Nedlands Western Australia
2School of Public Health, University of Sydney, Westmead, New South Wales, Australia
3School of Clinical Sciences, Faculty of Medicine, Nursing, and Health Sciences, Monash University, Clayton, Victoria, Australia
JAMA Intern Med. 2015;175(10):1720. doi:10.1001/jamainternmed.2015.3765.
Text Size: A A A
Published online


To the Editor The article by Uusi-Rasi and colleagues1 raises important considerations in the study design of randomized clinical trials on the effect of vitamin D on falling. It is clear from many randomized clinical trials that the role of vitamin D supplementation on falling—if it has a role—is likely to be found in subsets of the falling population.2 It is unfortunate that the study design did not take advantage of previous study findings.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





October 1, 2015
Kirsti Uusi-Rasi, PhD; Radhika Patil, MSc; Kari Tokola, MSc
1The UKK Institute for Health Promotion Research, Tampere, Finland2Department of Research, Tampere University Hospital, Tampere, Finland
1The UKK Institute for Health Promotion Research, Tampere, Finland
JAMA Intern Med. 2015;175(10):1720-1721. doi:10.1001/jamainternmed.2015.3768.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...