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Comment & Response |

Hyperbaric Oxygen Treatment for Persistent Postconcussion Symptoms—A Placebo Effect?

Pierre Marois, MD, FRCPC1,2; Arun Mukherjee, MBBS, MD3,4; Laurent Ballaz, PhD5
[+] Author Affiliations
1Department of Pediatrics, Ste-Justine University Hospital, Montreal, Quebec, Canada
2Department of Rehabilitation, Ste-Justine University Hospital, Montreal, Quebec, Canada
3National Heart Institute, East of Kailash, New Delhi, India
4Fortis C-DOC Hospital, Chirag Enclave, New Delhi, India
5Department of Kinanthropology, Université du Quebec, Montreal, Quebec, Canada
JAMA Intern Med. 2015;175(7):1239-1240. doi:10.1001/jamainternmed.2015.1032.
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To the Editor As coauthors of a recent study1 on hyperbaric treatment for children with cerebral palsy (CP), we would like to comment on the editorial by Hoge and Jonas2 published in JAMA Internal Medicine. Based on the study by Miller et al,3 they draw definitive conclusions on the efficacy of compressed air and hyperbaric oxygen treatment (HBOT) for postconcussion symptoms in military personnel: that HBOT does not work, but the ritual of intervention does. Although they2 recognized that both groups treated in hyperbaric chambers had significant improvements in postconcussion symptoms and secondary outcomes compared with the control group, they2 failed to reach the most evident conclusion: that both treatments were effective.


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July 1, 2015
R. Scott Miller, MD; Lindell K. Weaver, MD; Lisa A. Brenner, PhD
1Uniformed Services University of the Health Sciences, Bethesda, Maryland
2LDS Hospital, Salt Lake City, Utah3University of Utah School of Medicine, Salt Lake City
4Veterans Integrated Service Network 19, Mental Illness Research Education and Clinical Center, Denver, Colorado5University of Colorado Anschutz Medical Campus, Aurora
JAMA Intern Med. 2015;175(7):1240-1241. doi:10.1001/jamainternmed.2015.1048.
July 1, 2015
Charles W. Hoge, MD; Wayne B. Jonas, MD
1Center for Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, Maryland
2Samueli Institute, Alexandria, Virginia
JAMA Intern Med. 2015;175(7):1241. doi:10.1001/jamainternmed.2015.1051.
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