We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editorial |

Resistance to Antituberculosis Medications Hard Lessons to Learn

Donald A. Enarson, MD
Arch Intern Med. 2000;160(5):581-582. doi:10.1001/archinte.160.5.581.
Text Size: A A A
Published online


TWO ARTICLES concerning drug resistance in patients from Mexico published in this issue of the ARCHIVES1,2 highlight key challenges to a global strategy for tuberculosis control.

Mexico has clearly reduced the tuberculosis problem from historically higher levels,3 evidenced by the character of the current epidemiological picture of the disease as primarily affecting older men and high-risk groups.2 Despite recommendations by international authorities, the policies implemented thus far appear limited and in need of revision if Mexico is to achieve success against tuberculosis. This is evidenced by the high proportion of the most highly infectious (smear-positive) patients who have already gone through the system without having been permanently cured, a relatively high level of resistance to the medications available for treatment, and the consequent negative impact on treatment results. Furthermore, the failure to implement a unified surveillance system for all tuberculosis cases in the country limits the ability of the government itself to detect the consequences of the inappropriate policies that are currently in place. Finally, and most importantly, much of this could have been avoided1 if the government had adopted or would fully adopt the recommendations of international scientific bodies4,5 for the treatment of tuberculosis patients.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

3 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections
PubMed Articles