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Comment & Response |

Sex-Specific Chest Pain Characteristics

Manon G. van der Meer, MD1; Hendrik M. Nathoe, MD, PhD1; Yolande Appelman, MD, PhD2
[+] Author Affiliations
1Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands
2Department of Cardiology, VU University Medical Center Amsterdam, Amsterdam, the Netherlands
JAMA Intern Med. 2015;175(4):650. doi:10.1001/jamainternmed.2014.8060.
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To the Editor Rubini Gimenez et al1 studied sex-specific chest pain characteristics (CPCs) with the objective of improving the management of women with suspected acute myocardial infarction (AMI). They collected an impressive number of baseline and chest pain characteristics in a large sample of patients with chest pain.

Unfortunately, the prevalence of CPCs in women was only compared with the prevalence of CPCs in men. Whether the prevalence of CPCs in women with AMI differed from women without AMI (and men with and without AMI) was not evaluated, while such an analysis would demonstrate which symptoms are related to AMI in women and which in men.


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April 1, 2015
Maria Rubini Gimenez, MD; Raphael Twerenbold, MD; Christian Mueller, MD
1Department of Cardiology, University Hospital Basel, Basel, Switzerland
JAMA Intern Med. 2015;175(4):650. doi:10.1001/jamainternmed.2014.8075.
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