0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Invited Commentary |

Vitamin D and Falls—Fitting New Data With Current Guidelines

Erin S. LeBlanc, MD, MPH1; Roger Chou, MD2,3
[+] Author Affiliations
1Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon
2Pacific Northwest Evidence-based Practice Center, Oregon Health & Science University, Portland
3Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland
JAMA Intern Med. 2015;175(5):712-713. doi:10.1001/jamainternmed.2015.0248.
Text Size: A A A
Published online

Extract

Vitamin D is of great interest to the medical and lay communities. Numerous observational studies (often cross-sectional) have examined the association between serum levels of 25-hydroxyvitamin D (25[OH]D) and various conditions. Low levels of 25(OH)D have been associated with increased risk of falls, fractures, cardiovascular disease, colorectal cancer, type 2 diabetes mellitus, depressed mood, cognitive decline, and mortality.1 However, such studies are subject to potential confounding and bias, and whether vitamin D supplementation reduces the risks of acquiring any of these conditions is less clear. Randomized clinical trials (RCTs) have not shown that vitamin D supplementation improves health, except in persons at high risk of falling, for which some studies14 have demonstrated a decreased risk of falls. Based on this evidence, the US Preventive Services Task Force5 (USPSTF) and the American Geriatric Society6 recommend vitamin D supplementation for persons who are at high risk of falls.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure.
Vitamin D Supplementation vs Placebo and Risk of Falls, Stratified by Baseline Vitamin D Level

The analysis was conducted with Review Manager 5.2 (http://review-manager.software.informer.com/5.2/). Data from Porthouse et al9 and Uusi-Rasi et al7 were obtained from the study authors, while data for the other trials were from published reports. Vitamin D levels were not measured in Porthouse et al,9 and the patients were recruited from primary care clinics. M-H indicates Mantel-Haenszel. To convert serum 25-hydroxyvitamin D level to nanomoles per liter, multiply by 2.496.

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

2,392 Views
3 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections
PubMed Articles
Jobs
JAMAevidence.com

Care at the Close of Life: Evidence and Experience
Exercise

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed
An Illustration of Bias and Random Error

brightcove.createExperiences();