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The Numb Chin Syndrome: A Critical Sign for Primary Care Physicians

Jon M. Sweet, MD
Arch Intern Med. 2004;164(12):. doi:10.1001/archinte.164.12.1347.
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Charles Bell initially described the numb chin syndrome (NCS) in 1830. Although the syndrome is frequently described in the dental, oncology, and neurology literature, its importance as a symptom of underlying, progressing, or relapsing malignant disease remains unrecognized by most primary care physicians. Below is a case of Burkitt cell acute lymphoblastic leukemia presenting with NCS as both an initial manifestation of the disease and its subsequent relapse.

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