We read with interest the recent review by Felson and Anderson1 titled "Hyaluronate Sodium Injections for Osteoarthritis: Hope, Hype, and Hard Truths," published in the February issue of the ARCHIVES. In contrast to the review, we find that intra-articular hyaluronan (HA) is an effective therapy for reducing pain associated with osteoarthritis (OA) of the knee for many of our patients. Hyaluronan is a safe and efficacious treatment modality that has been confirmed in numerous controlled clinical studies. We believe that many of the so-called hard truth(s) in this review are misleading.
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