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Editor's Correspondence |

Chronic Back Pain: A Symptom in Search of a Diagnosis—Reply

Stephen M. Salerno, MD, MPH; Jeffrey L. Jackson, MD, MPH
Arch Intern Med. 2002;162(11):1310-1311. doi:.
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Dr Johnston raises important concerns about the methodology of existing treatment studies of chronic low back discomfort. He suggests that antidepressants may be particularly effective in some subgroups of patients, but not effective at all in others. While all of the 9 studies we discussed included patients with multiple diagnoses for low back discomfort, 8 examined or imaged patients prior to enrollment. In their exclusion criteria or results section, they did not include patients with malignancy, structural disorders requiring surgery, or pain from nonrelated systemic disorders outside the back area.1

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Correspondence

June 10, 2002
Stephen M. Salerno, MD, MPH; Jeffrey L. Jackson, MD, MPH
Arch Intern Med. 2002;162(11):1310-1311. doi:.
June 10, 2002
Albert W. Wu, MD, MPH; Gregory Diette, MD, MHS; Yuchi Young, PhD
Arch Intern Med. 2002;162(11):1310-1311. doi:.
June 10, 2002
Mirella Fraquelli, MD, PhD; Alice Colucci, MD; Silvia Paggi, MD; Dario Conte, MD
Arch Intern Med. 2002;162(11):1310-1311. doi:.
June 10, 2002
Emmanuel Andrès, MD; Frédéric Maloisel, MD
Arch Intern Med. 2002;162(11):1310-1311. doi:.
June 10, 2002
Elbert S. Huang, MD, MPH; Randall S. Stafford, MD, PhD
Arch Intern Med. 2002;162(11):1310-1311. doi:.
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