Accepted for Publication: September 14, 2014.
Published Online: January 19, 2015. doi:10.1001/jamainternmed.2014.6294.
Study concept and design: Ray, Chung, Murray, Cooper, Stein.
Acquisition, analysis, or interpretation of data: Chung, Murray, Cooper, Hall.
Drafting of the manuscript: Ray, Murray, Stein.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Ray.
Obtained funding: Ray, Murray, Stein.
Administrative, technical, or material support: Ray, Chung, Murray, Hall, Stein.
Study supervision: Ray, Chung, Cooper, Stein.
Conflict of Interest Disclosures: None reported.
Funding/Support: The study was supported by a grant from the National Heart, Lung, and Blood Institute (HL081707), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (K23AR064768), and a Vanderbilt Physician Scientist Development award (Dr Chung).
Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We gratefully acknowledge the Tennessee Bureau of TennCare, the Tennessee Department of Health, and Tennessee Donor Services, which provided study data.