Accepted for Publication: September 27, 2014.
Published Online: January 5, 2015. doi:10.1001/jamainternmed.2014.6283.
Study concept and design: Wu, Willett, Hu, Sun.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Wu, Qi, Sampson, Hu.
Critical revision of the manuscript for important intellectual content: Wu, Flint, Qi, van Dam, Rimm, Holmes, Willett, Hu, Sun.
Statistical analysis: Wu, Qi, Willett, Sun.
Obtained funding: Holmes, Willett, Hu.
Administrative, technical, or material support: Flint, Sampson, Rimm, Hu.
Study supervision: Willett, Hu, Sun.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported by research grants R01 DK58845 (Dr Hu), P01 CA87969, R01 HL034594, UM1 CA167552 (Dr Willett), R01 HL35464 (Dr Rimm), HL60712 (Dr Hu), U54CA155626 (Dr Hu), and CA055075 from the National Institutes of Health and Career Development Award R00HL098459 from the National Heart, Lung, and Blood Institute (Dr Sun).
Role of the Funder/Sponsor: The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and the decision to submit the manuscript for publication.
Additional Contributions: The participants and staff of the NHS and HPFS and the following state cancer registries provided valuable contributions: Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Nebraska, New Hampshire, New Jersey, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Virginia, Washington, and Wyoming. In addition, this study was approved by the Connecticut Department of Public Health Human Investigations Committee. Certain data used in this publication were obtained from the Connecticut Department of Public Health.