Accepted for Publication: September 29, 2014.
Published Online: December 8, 2014. doi:10.1001/jamainternmed.2014.6573.
Study concept and design: Vora, Wang.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Vora, Rokos, Roe, Granger, French, Antman, Henry, Thomas, Bates, Wang.
Critical revision of the manuscript for important intellectual context: All authors.
Statistical analysis: Holmes, Thomas.
Conflict of Interest Disclosures: Dr Rokos reported consulting for the Mission: Lifeline STEMI Accelerator program. Dr Roe reported research funding from Eli Lilly & Company, Daiichi-Sankyo, Bristol-Myers Squibb, Hoffmann-La Roche, Novartis, Schering Plough, KAI Pharmaceuticals, and sanofi-aventis; educational activities or lectures for AstraZeneca and Janssen Pharmaceuticals; and consulting for Bristol-Myers Squibb, GlaxoSmithKline, Merck, Janssen Pharmaceuticals, KAI Pharmaceuticals, sanofi-aventis, Helsinn Pharmaceuticals, Regeneron, Novartis, AstraZeneca, and Orexigen. Dr Granger reported research funding from Boehringer Ingelheim, Bristol-Myers Squibb, GlaxoSmithKline, Medtronic, Merck, Pfizer, sanofi-aventis, Takeda, and The Medicines Company, as well as consulting for Boehringer Ingelheim, Bristol-Myers Squibb, GlaxoSmithKline, Hoffmann-La Roche, Eli Lilly & Company, Pfizer, sanofi-aventis, Takeda, The Medicines Company, AstraZeneca, Daiichi-Sankyo, and Ross Medical Corporation. Dr Wang reported research funding from AstraZeneca, Daiichi-Sankyo, Gilead, GlaxoSmithKline, Eli Lilly & Company, and the American College of Cardiology; consulting for AstraZeneca; and educational activities from the American College of Cardiology Foundation. No other disclosures were reported.
Funding/Support: This research was supported by the American College of Cardiology Foundation’s National Cardiovascular Data Registry and by the American Heart Association’s Mission: Lifeline program. The ACTION Registry-GWTG is an initiative of the American College of Cardiology Foundation and the American Heart Association, with partnering support from the Society of Chest Pain Centers, the American College of Emergency Physicians, and the Society of Hospital Medicine.
Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The views expressed in this article represent those of the authors and do not necessarily represent the official views of the National Cardiovascular Data Registry or its associated professional societies identified at http://www.ncdr.com .
Additional Contributions: We thank Erin Hanley, BA, Duke Clinical Research Institute, for editorial assistance and Chirag Tamboli for data entry assistance. Ms Hanley did not receive compensation for her assistance apart from her employment at Duke Clinical Research Institute. Mr Tamboli did not receive compensation for his assistance.