We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Research Letter |

Variation in Inpatient Costs of Hematopoietic Cell Transplantation Among Transplant Centers in the United States

Viengneesee Thao, MS1; Katy B. Kozhimannil, PhD1; Will Thomas, PhD2; Ezra Golberstein, PhD1
[+] Author Affiliations
1Division of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis
2Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis
JAMA Intern Med. 2014;174(8):1409-1412. doi:10.1001/jamainternmed.2014.2302.
Text Size: A A A
Published online


Hematopoietic cell transplantation (HCT) using the patient’s own (autologous) or a donor’s (allogeneic) HCT progenitor cells is a highly effective but costly therapy for life-threatening blood disorders and cancers. Despite the small number of annual procedures (20 000 a year in the United States), HCT hospitalization spending increased from $684 million to $1.3 billion between 2004 and 2007, placing it among the procedures with the most rapid spending increases.1 Those increases reflect rising procedure volume and rising hospitalization costs.1 Prior research2 on HCT costs has been limited to single-institution analyses. To quantify variation in costs of HCT across hospitals, we analyzed data from the Nationwide Inpatient Sample (NIS),3 the largest hospital database with charge information on all patients admitted to the sampled hospitals regardless of payer.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption
Adjusted Ranked Hospital Mean Costs of Autologous and Allogeneic Hematopoietic Cell Transplantation (HCT), 2008-2010

Hospital geometric means are shown for autologous (n = 32) (A) and allogeneic (n = 22) (B) HCTs. The size of the plotting character is proportional to the hospital’s total volume of HCT cases. Hospitals in the highest and lowest quintile are indicated with squares. The lines across the graphs indicate the overall adjusted mean. Limit lines indicate 95% CI.

Graphic Jump Location




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

1 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles