Accepted for Publication: November 9, 2013.
Published Online: June 2, 2014. doi:10.1001/jamainternmed.2014.1600.
Study concept and design: Preston, Morash, Giovannucci, Mucci, Olumi.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Preston, Wilson, Loda, Mucci, Olumi.
Critical revision of the manuscript for important intellectual content: Wilson, Markt, Ge, Morash, Stampfer, Giovannucci, Mucci, Olumi.
Statistical analysis: Preston, Wilson, Markt, Olumi.
Obtained funding: Preston, Morash, Loda, Giovannucci, Mucci, Olumi.
Administrative, technical, or material support: Stampfer, Loda, Olumi.
Study supervision: Morash, Stampfer, Loda, Mucci, Olumi.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported by funding from the National Cancer Institute at the National Institutes of Health (NIH) (grants P01 CA055075 and CA133891); NIH training grants T32 CA09001 (Dr Wilson) and R25 CA098566 (Dr Markt); the Prostate Cancer Foundation (Dr Mucci); NIH grant R01-DK 091353 (Dr Olumi); and the Urology Care Foundation Research Scholar Program and the Robert J. Krane, MD, Urology Research Scholar Fund (Dr Preston).
Role of the Sponsors: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Previous Presentations: This study was presented at the American Urological Association Meeting; May 5, 2013; San Diego, California; and at the Canadian Urological Association Meeting; June 23, 2013; Niagara Falls, Ontario, Canada.
Additional Contributions: We are grateful to the ongoing participation of men in the Health Professionals Follow-up Study (UM1 CA167552) and would like to acknowledge our colleagues (Lauren McLaughlin, BA, and Siobhan Saint-Surin, MA) working on these studies for their valuable help. We are grateful to Walter Willett for his expert comments and advice. In addition we would like to thank the following state cancer registries for their help: Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Nebraska, New Hampshire, New Jersey, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Virginia, Washington, Wyoming.
Additional Information: This study was approved by the Connecticut Department of Public Health (DPH) Human Investigations Committee. Certain data used in this publication were obtained from the DPH. The Connecticut DPH information was just used for disease follow-up among people in the study from Connecticut.