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Research Letter |

Decade-Long Trends in Mortality Among Patients With and Without Diabetes Mellitus at a Major Academic Medical Center

Neel M. Butala, AB1; Benjamin K. Johnson, MA2; James D. Dziura, PhD2; Jesse S. Reynolds, MS2; Thomas J. Balcezak, MD, MPH3,4,5; Silvio E. Inzucchi, MD6; Leora I. Horwitz, MD, MHS4,7
[+] Author Affiliations
1Medical student at Yale School of Medicine, New Haven, Connecticut
2Yale Center for Analytical Sciences, School of Public Health, Yale University, New Haven, Connecticut
3Yale–New Haven Hospital, New Haven, Connecticut
4Section of General Internal Medicine, Department of Medicine, Yale School of Medicine, New Haven, Connecticut
5School of Public Health, Yale University, New Haven, Connecticut
6Section of Endocrinology, Department of Medicine, Yale School of Medicine, New Haven, Connecticut
7Center for Outcomes Research and Evaluation, Yale–New Haven Hospital, New Haven, Connecticut
JAMA Intern Med. 2014;174(7):1187-1188. doi:10.1001/jamainternmed.2014.1803.
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The prevalence of diabetes mellitus has risen markedly over the past decade and is projected to increase substantially.1 More than 20% of hospitalized patients are estimated to have diabetes,2 and individuals with diabetes have historically experienced higher inpatient mortality than individuals without diabetes.3 Over the past decade, evidence from large clinical trials has prompted recommendations for tighter inpatient and outpatient glucose control, as well as more stringent blood pressure and lipid management, to improve outcomes for patients with diabetes.46 It is unclear whether the mortality impact of diabetes has changed as a consequence.

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Unadjusted Mortality Trends Among Patients With and Without Diabetes Mellitus, 2000 Through 2010
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