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Comment & Response |

Caution Warranted When Defining Contraindications in Initiating β-Blocker Therapy

Marta A. Miyares, PharmD, BCPS1
[+] Author Affiliations
1Department of Pharmacy, Jackson Memorial Hospital, Miami, Florida
JAMA Intern Med. 2014;174(3):481. doi:10.1001/jamainternmed.2013.13698.
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To the Editor Dharmarajan and colleagues1 are to be commended for their review of hospitalized patients with acute decompensated heart failure initiated on β-blocker therapy during predefined periods of clinical instability, which showed that at least 40% of those initiated had at least 1 possible contraindication (care in an intensive care unit, administration of intravenous loop diuretic on the day of discharge, or having received an intravenous inotrope during hospitalization).


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March 1, 2014
Kumar Dharmarajan, MD, MBA; Harlan M. Krumholz, MD, SM
1Division of Cardiology, Columbia University Medical Center, New York, New York2Center for Outcomes Research and Evaluation, Yale–New Haven Hospital, New Haven, Connecticut
2Center for Outcomes Research and Evaluation, Yale–New Haven Hospital, New Haven, Connecticut3Section of Health Policy and Administration, Yale School of Public Health, New Haven, Connecticut4Robert Wood Johnson Clinical Scholars Program, Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut
JAMA Intern Med. 2014;174(3):481-482. doi:10.1001/jamainternmed.2013.13685.
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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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