Comment & Response |

Conflicts of Interest in Approvals of Food Additives—Reply

Thomas G. Neltner, JD1; Maricel V. Maffini, PhD1
[+] Author Affiliations
1Natural Resources Defense Council, Washington, DC
JAMA Intern Med. 2014;174(2):300-301. doi:10.1001/jamainternmed.2013.12686.
Text Size: A A A
Published online


In Reply Clemens and Schmidt imply that a conflict of interest is synonymous with a lack of scientific integrity. The Institute of Medicine (IOM) report concluded that no matter how careful an individual is, conflicts may compromise a scientist’s objective analysis consciously or unconsciously, potentially resulting in a poor decision.1

Clemens and Schmidt also assert, without substantiation, that transparency and conflicts of interest standards may “compromise food safety through empaneling less-experienced reviewers.” If true that too few competent scientists are without serious conflicts, perhaps the close-knit network that makes many of the determinations about additives to food “Generally Recognized as Safe” (GRAS) has become stagnant and needs to grow.


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





February 1, 2014
Leon Bruner, DVM, PhD
1Science and Regulatory Affairs, The Grocery Manufacturers Association, Washington, DC
JAMA Intern Med. 2014;174(2):299. doi:10.1001/jamainternmed.2013.12720.
February 1, 2014
Roger Clemens, DrPH; David Schmidt
1International Center for Regulatory Science, University of Southern California School of Pharmacy, Los Angeles
2International Food Information Council, Washington, DC
JAMA Intern Med. 2014;174(2):299-300. doi:10.1001/jamainternmed.2013.12723.
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...