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Comment & Response |

Vertebral Augmentation for Symptomatic Compression Fractures Is Supported by Randomized Clinical Trials

Jason R. Levy, MD1; Douglas P. Beall, MD2
[+] Author Affiliations
1Department of Interventional Radiology, Northside Hospital, Atlanta, Georgia
2Clinical Radiology of Oklahoma, Edmond
JAMA Intern Med. 2014;174(2):307. doi:10.1001/jamainternmed.2013.13035.
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To The Editor We read with interest the Invited Commentary by Dr Bauer.1 We believe there are portions of his comments that lack scientific support.

The author states that “Although uncontrolled studies have consistently demonstrated reduced short-term pain and disability after vertebral augmentation, randomized trial results have been inconsistent.”1(p1522) In fact, if all Oxford level I and level II data are considered, there are 27 studies, including 8 randomized clinical trials. This collection of articles shows significant reductions in pain, improvement in quality of life, fewer subsequent fractures, and greater kyphosis reduction.2


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February 1, 2014
Rita F. Redberg, MD, MSc
JAMA Intern Med. 2014;174(2):308. doi:10.1001/jamainternmed.2013.13025.
February 1, 2014
Douglas C. Bauer, MD
1Department of Medicine, University of California, San Francisco2Department of Epidemiology and Biostatistics, University of California, San Francisco
JAMA Intern Med. 2014;174(2):307-308. doi:10.1001/jamainternmed.2013.13024.
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