Research Letter |

Use and Yield of Endoscopy in Patients With Uncomplicated Gastroesophageal Reflux Disorder

Jennifer R. Kramer, PhD, MPH1,3; Mohammad H. Shakhatreh, MD1,2,4; Aanand D. Naik, MD1,2,3; Zhigang Duan, MD, MS1,3; Hashem B. El-Serag, MD, MPH1,2,4
[+] Author Affiliations
1Center for Innovations in Quality, Effectiveness, and Safety, VA Health Services Research & Development, Washington, DC
2Department of Medicine, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas
3Section of Health Services Research, Department of Medicine, Baylor College of Medicine, Houston, Texas
4Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas
JAMA Intern Med. 2014;174(3):462-465. doi:10.1001/jamainternmed.2013.13015.
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Practice guidelines recommend esophagogastroduodenoscopy (EGD) screening for Barrett esophagus (BE) or esophageal cancer for patients with uncomplicated gastroesophageal reflux disease (GERD), especially in high-risk patients (symptoms for >5 years, white race, male sex, age >50 years, and family history of BE or esophageal cancer).1,2 However, the extent of using screening EGD, its predictors, and diagnostic yield are unclear. We aimed to determine prevalence, predictors, and yield of screening EGD in a large national sample of patients with uncomplicated GERD.

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