Comment & Response |

Dietary and Supplemental Calcium Intake and Mortality—Reply

Qian Xiao, PhD1; Yikyung Park, ScD1
[+] Author Affiliations
1Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch, National Cancer Institute, Rockville, Maryland
JAMA Intern Med. 2013;173(19):1841-1842. doi:10.1001/jamainternmed.2013.9232.
Text Size: A A A
Published online


In Reply In their study of a Hong Kong Chinese population, whose calcium intake is substantially lower than the Western population, Chan et al reported there was a protective effect of dietary calcium intake on total mortality and cardiovascular mortality. The lower cutoff of their highest intake category (>762 mg/d for men and >668 mg/d for women) are around the median intake values (739 mg/d for men and 648 mg/d for women) found in our US cohort. As shown in Figure 2 of our article,1 we observed a nonlinear association between total calcium intake and total cardiovascular disease mortality in men: risk decreased at a calcium intake up to approximately 1200 mg/d, but started to increase at an intake of 1500 mg/d and higher. Therefore, a study with population that has relatively low calcium intake and narrow range of intake is likely to observe an inverse association between calcium intake and mortality, especially cardiovascular disease mortality.


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





October 28, 2013
Elke Theuwissen, PhD; Vladimir Badmaev, MD, PhD; Cees Vermeer, PhD
1VitaK, Maastricht University, the Netherlands
2NattoPharma ASA, Oslo, Norway
JAMA Intern Med. 2013;173(19):1841. doi:10.1001/jamainternmed.2013.9260.
October 28, 2013
Robert Colgrove, MD
1Division of Infectious Diseases, Mount Auburn Hospital, Cambridge, Massachusetts
JAMA Intern Med. 2013;173(19):1840. doi:10.1001/jamainternmed.2013.9267.
October 28, 2013
Ruth Chan, PhD; Jason Leung, MSc; Jean Woo, MD
1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region
2Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong Special Administrative Region
JAMA Intern Med. 2013;173(19):1840. doi:10.1001/jamainternmed.2013.9276.
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...