Accepted for Publication: February 21, 2013.
Published Online: June 10, 2013. doi:10.1001/jamainternmed.2013.6465.
Acquisition of data: Frikke-Schmidt, Nordestgaard, Tybjærg-Hansen.
Analysis and interpretation of data: Stender, Nordestgaard, Tybjærg-Hansen.
Drafting of the manuscript: Stender.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Stender.
Obtained funding: Nordestgaard, Tybjærg-Hansen.
Administrative, technical, and material support: Frikke-Schmidt, Nordestgaard, Tybjærg-Hansen.
Study supervision: Frikke-Schmidt, Tybjærg-Hansen.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported by grant 10-083788 from the Danish Medical Research Council, the Research Fund at Rigshospitalet, Copenhagen University Hospital, Chief Physician Johan Boserup and Lise Boserup’s Fund, Ingeborg and Leo Dannin’s Grant, Henry Hansen and Wife’s Grant, and a grant from the Odd Fellow Order.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: We are indebted to the staff and participants of the Copenhagen General Population Study and the Copenhagen City Heart Study for their important contributions to our study.