2013 Brings many changes for JAMA Internal Medicine (first, our new name) as well as for the country. I began my editorship 4 years ago announcing a new focus on health care reform at the same time our new President began his first term. Under our Health Care Reform banner, we have published widely cited articles on insurance coverage, use of medical devices and pharmaceuticals, health care costs, and delivery system changes. We will keep you informed on how the foldout of the many Patient Protection and Affordable Care Act provisions, such as coverage expansion, insurance exchanges, and accountable care, are affecting our delivery of health care. We are delighted with the growing national conversation on appropriate care and how to decrease inappropriate or harmful care and the role of the Less Is More series in informing this conversation. We plan to continue to publish high-quality scientific articles, vignettes, and commentaries that can improve patient care, inform practice, and lead to better patient outcomes, and we welcome your contributions.