Accepted for Publication: January 14, 2013.
Published Online: April 1, 2013. doi:10.1001/jamainternmed.2013.189
Author Contributions: Dr Barnes had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analyses. Study concept and design: Barnes, Kramer, and Yaffe. Acquisition of data: Barnes, Santos-Modesitt, Poelke, and Middleton. Analysis and interpretation of data: Barnes, Poelke, Castro, Middleton, and Yaffe. Drafting of the manuscript: Barnes. Critical revision of the manuscript for important intellectual content: Barnes, Poelke, Santos-Modesitt, Kramer, Castro, Middleton, and Yaffe. Statistical analysis: Barnes, Poelke, and Middleton. Obtained funding: Barnes. Administrative, technical, and material support: Barnes, Santos-Modesitt, Poelke, Kramer, and Castro. Study supervision: Barnes, Santos-Modesitt, and Yaffe.
Conflict of Interest Disclosures: Computers, software, and DVDs were donated by Posit Science, and exercise space and equipment were donated by the Stonestown YMCA, both in San Francisco.
Funding/Support: This study was funded through a Career Development Award from the National Institute on Aging (grant K01-AG024069), the Alzheimer's Association (grant IIRG-06-27306), the University of California School of Medicine, and the Institutes of Health/National Center for Research Resources/University of California, San Francisco–Clinical and Translational Science Institute (grant KL2 RR024130).
Disclaimer: The contents of this article are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health.
Previous Presentation: Findings from this study were presented at the International Conference on Alzheimer's Disease; Honolulu, Hawaii; July 14, 2010.
Additional Contributions: We thank the study participants. In addition, we thank the following individuals: staff research assistants Wanda Rieman, PhD, Jacy Leonardo, PhD, and Ellie Shirgul, PsyD; database manager Gary Tarasovsky, MA; data analyst Katharine Kirby, MA; research volunteers Yani Leyva, PhD, Serena Galloway, PhD, Gabrielle Gotta, PhD, Ann Tran, PhD, Todd Rising, PhD, and Andrew Bloch, PsyD; summer interns Sierra Ford, BA, and William Goodson, BA; exercise instructor Ray Hanvey, BA; YMCA facilitator Becky Hanvey, BA; and Data Monitoring Committee members Mark Espeland, PhD; George Rebok, PhD; and Rebecca Sudore, MD.