Accepted for Publication: September 8, 2012.
Published Online: January 7, 2013. doi:10.1001/jamainternmed.2013.1632
Author Contributions: Dr Liu had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Liu, Mei, and Cogswell. Acquisition of data: Liu, Mei, and Ren. Analysis and interpretation of data: Liu, Mei, Ye, Serdula, Ren, and Cogswell. Drafting of the manuscript: Liu, Mei, Serdula, and Cogswell. Critical revision of the manuscript for important intellectual content: Liu, Mei, Ye, Serdula, Ren, and Cogswell. Statistical analysis: Liu and Mei. Obtained funding: Liu, Mei, and Cogswell. Administrative, technical, and material support: Liu, Mei, Ye, Serdula, Ren, and Cogswell. Study supervision: Liu, Mei, Ren, and Cogswell.
Conflict of Interest Disclosures: None reported.
Funding/Support: The study is supported by a cooperative agreement between Peking University Health Science Center and the Centers for Disease Control and Prevention.
Role of the Sponsor: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of Centers for Disease Control and Prevention. The sponsor had a role in study design, data collection, data analysis and interpretation, and writing of the report.
Additional Contributions: We are grateful to all study participants and the hundreds of health care workers from Yuanshi, Mancheng, Xianghe, Fengrun, and Laoting counties in China who made the project possible. We thank Wei-cheng You, MD, Michael A. Brown, MPH, Ibrahim Parvanta, MS, Robert J. Berry, MD, and Jacqueline Gindler, MD, and the members of the data safety and monitoring board (Michael J. Dibley [chair], MPH, Sean Lynch, PhD, Christine McClaren, PhD, Shuigao Jin, PhD, and Zhenglai Wu, MD) for their support of this project. We also thank Zhiwen Li, PhD, Hongtian Li, MD, Lei Jin, PhD, Le Zhang, PhD, Linlin Wang, PhD, Quangang Qu, PhD,Yali Zhang, PhD, Juan Wang, MD, Weixian Gao, BS, Zheng Yao, MD, and all other staff who have currently or previously worked on the project at the Peking University Institute of Reproductive and Child Health.