0
Invited Commentary |

An Intersection of Atrial Fibrillation With Sudden Death:  Look Both Ways, and Proceed With Caution
Comment on “Atrial Fibrillation and the Risk of Sudden Cardiac Death”

Kyndaron Reinier, PhD, MPH; Sumeet S. Chugh, MD
JAMA Intern Med. 2013;173(1):35-37. doi:10.1001/jamainternmed.2013.1774.
Text Size: A A A
Published online

Extract

Atrial fibrillation (AF) is the most common arrhythmia in the world, with established public health implications due to increased morbidity, hospitalization, and health care costs.1 Both incidence and prevalence appear to be on the rise, with an annual US incidence of 3.7 per 1000 person-years in 2000.2 Sudden cardiac death (SCD) is the most devastating manifestation of cardiac ventricular electrical arrhythmias; more than 95% of individuals will experience an SCD within 10 minutes of presenting with ventricular tachycardia, ventricular fibrillation, pulseless electrical activity, or asystole.3 Despite advances in prevention and management of sudden cardiac arrest, 300 000 to 350 000 US lives are lost annually due to SCD, constituting approximately 50% of overall mortality from cardiovascular disease.4 As a consequence, the potential intersection of these two important conditions has long been of interest to investigators in either field. While an independent relationship between AF and overall mortality has been reported,5 an independent association between AF and the subgroup of patients with SCD had not been demonstrated.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Topics
PubMed Articles
Jobs
JAMAevidence.com

Users' Guides to the Medical Literature
Clinical Resolution

Users' Guides to the Medical Literature
Clinical Scenario

brightcove.createExperiences();