The data are from a national mail survey of 1504 US primary care physicians (those with a primary specialty of general internal medicine, family medicine, or general practice, and with no secondary specialty) who were 65 years or younger. The survey was conducted from 2009 to 2010. The overall response rate was 63% after excluding 77 primary care physicians who had invalid addresses or were no longer practicing. Data were weighted to represent the population of US primary care physicians. A more detailed description of the research design is presented elsewhere.7 Outcome measures were questions about how much personal satisfaction physicians experience when taking care of patients with alcoholism, obesity, and nicotine dependence. With respect to predictors, physicians were asked to indicate for each condition to the extent to which the condition resulted from choices for which patients are responsible. Career satisfaction was measured as agreement or disagreement with the statement, “If I had it to do over again, I would not choose medicine as a career.” Finally, physicians were asked whether they agree or disagree with the statement, “For me, the practice of medicine is a calling.” We used separate multivariable logistic regression models to estimate independent effects of patient responsibility, physician career satisfaction, and practice of medicine as a calling on each of the 3 conditions. Physician specialty, sex, age, race/ethnicity, region, immigration status, religious affiliation, and importance of religion were also included as covariates in the models.