Published Online: June 18, 2012. doi:10.1001/archinternmed.2012.2271
Author Contributions: Dr Caglayan had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Caglayan, Hellmich, and Rosenkranz. Acquisition of data: Caglayan, Axmann, and Moinzadeh. Analysis and interpretation of data: Caglayan, Hellmich, and Rosenkranz. Drafting of the manuscript: Caglayan, Axmann, Hellmich, and Rosenkranz. Critical revision of the manuscript for important intellectual content: Caglayan, Hellmich, Moinzadeh, and Rosenkranz. Statistical analysis: Hellmich. Obtained funding: Rosenkranz. Administrative, technical, and material support: Caglayan, Moinzadeh, and Rosenkranz. Study supervision: Caglayan and Rosenkranz. Ms Axmann and Dr Moinzadeh assisted in the recruitment (Ms Axmann) and investigation (Dr Moinzadeh) of patients.
Financial Disclosure: None reported.
Funding/Support: This study was funded by Bayer Healthcare, Leverkusen, Germany, who provided the study medication and also in part by the German Federal Ministry of Research and Education (BMBF grant 01KN0706). We kindly acknowledge support by ZKS Köln (grant BMBF 01KN1106).
Role of the Sponsors: The sponsor had no role in the design and conduct of the study, in the collection, analysis, and interpretation of the data, or in the preparation, review, or approval of the manuscript.
Additional Contributions: Michael Huntgeburth, MD, contributed significantly to the study concept and design; Erland Erdmann, MD, Thomas Krieg, MD, and Nicolas Hunzelmann, MD, critically revised the manuscript for important intellectual content and provided administrative support.