Published Online: June 11, 2012. doi:10.1001/archinternmed.2012.2171
Author Contributions: Dr Golomb had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Golomb and Dimsdale. Acquisition of data: Golomb and White. Analysis and interpretation of data: Golomb, Evans, Dimsdale, and White. Drafting of the manuscript: Golomb, Dimsdale, and White. Critical revision of the manuscript for important intellectual content: Golomb, Evans, and Dimsdale. Statistical analysis: Golomb and White. Obtained funding: Golomb. Administrative, technical, and material support: Evans. Study supervision: Dimsdale.
Financial Disclosure: None reported.
Funding/Support: This study was funded by National Institutes of Health (NIH) grant RO1 HL63055 from the National Heart, Lung, and Blood Institute and was supported by the UCSD General Clinical Research Center (NIH grant MO1 RR00827).
Trial Registration: clinicaltrials.gov Identifier: NCT00330980
Additional Contributions: Janis B. Ritchie, BSN, Diana King, BS, and Julie O. Denenberg, MA, were study clinic manager, recruitment manager, and data manager, respectively, and were seminal to the smooth operations of the study. Study pharmacist Steve Funk, PharmD, managed pill and blinding allocations. Tom Cookson, PharmD, assisted in recruitment in early phases of the study. These individuals received payment for their involvement on the study. Sabrina Koperski provided administrative assistance. We sincerely thank the study subjects, without whom this study would not have been possible.