Accepted for Publication: December 21, 2011.
Published Online: February 27, 2012. doi:10.1001/archinternmed.2011.2275
Author Contributions: Dr Cutlip had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Novack, Pencina, Cohen, and Cutlip. Acquisition of data: Cohen and Cutlip. Analysis and interpretation of data: Novack, Pencina, Yen, Saucedo, Berger, and Cutlip. Drafting of the manuscript: Novack and Cutlip. Critical revision of the manuscript for important intellectual content: Novack, Pencina, Cohen, Yen, Saucedo, and Berger. Statistical analysis: Novack, Pencina, and Yen. Obtained funding: Cohen. Administrative, technical, and material support: Berger. Study supervision: Cutlip.
Financial Disclosure: Drs Novack and Pencina are consultants to and Mr Yen is an employee of Harvard Clinical Research Institute, a not-for-profit academic research organization that received grant support for data management and analysis of the EVENT registry. Dr Cohen is on the advisory boards for Medtronic and Cordis; has received consulting fees from Medtronic, Abbott Vascular, Volcano, Eli Lilly/Daiichi Sankyo, and St Jude; and has received grant support paid to his institution from Medtronic, Boston Scientific, Abbott Vascular, Eli Lilly/Daiichi Sankyo, Astra Zeneca, Med Rad, and Edwards Lifesciences. Dr Kleiman has served as a consultant to Eli Lilly/Daiichi Sankyo and has received research support paid to his institution from Schering Plough and Merck. Dr Saucedo has received consulting fees and grant support from Schering-Plough and Merck. Dr Berger has served as a consultant to AstraZeneca, Boehringer Ingelheim, Eli Lilly/Daiichi Sankyo, Medicure, Accumetrics, and Ortho McNeil and has received research funding paid to his institution from ThromboVision, Helena, Accumetrics, AstraZeneca, Haemoscope, The Medicines Company, and Corgenix. He owns equity in Lumen Inc. Dr Cutlip is a consultant to and receives academic salary support from Harvard Clinical Research Institute and has received research support paid to his institution from Medtronic.
Funding/Support: Funding for EVENT and analysis was provided by grants from Millennium Pharmaceuticals and Schering-Plough.
Role of the Sponsor: Neither sponsor participated in the design and conduct of the study; the collection, analysis, or interpretation of the data; or the preparation, review, or approval of the manuscript.