Author Contributions: Dr Buchman had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Buchman and Bennett. Acquisition of data: Buchman and Bennett. Analysis and interpretation of data: Buchman, Yu, Boyle, Shah, and Bennett. Drafting of the manuscript: Buchman. Critical revision of the manuscript for important intellectual content: Buchman, Yu, Boyle, Shah, and Bennett. Statistical analysis: Yu and Boyle. Obtained funding: Buchman and Bennett. Administrative, technical, and material support: Buchman and Bennett. Study supervision: Buchman and Bennett.
Financial Disclosure: None reported.
Funding/Support: The study was supported by National Institute on Aging grants R01AG17917, R01AG24480, and R01AG34374.
Additional Contributions: We are indebted to the participants and the staff of the Rush Memory and Aging Project and the Rush Alzheimer's Disease Center for this work.