Author Contributions: Study concept and design: Hajjar, Milberg, and Lipsitz. Acquisition of data: Hajjar and Hart. Analysis and interpretation of data: Hajjar, Chen, Mack, Chui, and Lipsitz. Drafting of the manuscript: Hajjar, Mack, and Lipsitz. Critical revision of the manuscript for important intellectual content: Hajjar, Hart, Chen, Mack, Milberg, Chui, and Lipsitz. Statistical analysis: Hajjar, Chen, and Mack. Obtained funding: Hajjar and Lipsitz. Administrative, technical, and material support: Hajjar, Hart, and Lipsitz. Study supervision: Hajjar, and Mack, Milberg, Chui, Lipsitz.
Financial Disclosure: None reported.
Funding/Support: Dr Hajjar and the Antihypertensives and Vascular, Endothelial and Cognitive Function (AVEC) Trial are supported by grant 1 K23 AG030057 from the National Institute on Aging (NIA). This work is also supported by NIA grants P01-AG004390 and R37-AG025037 given to Dr Lipsitz, the Irving and Edyth S. Usen and Family Chair in Geriatric Medicine at Hebrew SeniorLife; National Institutes of Health/National Center for Research Resources grant UL1RR031986 for the University of Southern California Clinical Translational Science Institutions and Dr Mack; and the generous donation from Hinda Marcus to the Cardiovascular Research Laboratory at Hebrew SeniorLife.
Trial Registration: clinicaltrials.gov Identifier: NCT00605072