Percutaneous coronary interventions (PCIs) are among the most common procedures performed in the United States, and 30-day readmission rates have become a publicly reported performance measure for quality of PCIs. Khawaja et al identified 15 498 PCIs (elective or for acute coronary syndromes) from January 1998 to June 2008 at Saint Marys Hospital, Rochester, Minnesota, including Medicare and other payer types. Overall, nearly 1 in 10 patients were readmitted within 30-days after PCI, and the majority (69%) of readmissions were related to a cardiac reason. After multivariable analysis, female sex, Medicare insurance, less than a high school education, unstable angina, stroke or transient ischemic attack, moderate to severe renal disease, chronic obstructive pulmonary disease, peptic ulcer disease, metastatic cancer, and a length of stay longer than 3 days were associated with an increased risk of 30-day readmission after PCI. Patients who were readmitted within 30 days of discharge were at an increased risk of 1-year mortality compared with those who were not readmitted (adjusted hazard ratio, 1.38; 95% CI, 1.08-1.75 [P = .009]).