Accepted for Publication: September 7, 2011.
Published Online: November 14, 2011. doi:10.1001/archinternmed.2011.555
Author Contributions: Dr McBeth had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: McBeth, Prescott, Lovell, Keeley, McNamee, Symmons, Woby, and Macfarlane. Acquisition of data: McBeth, Keeley, Woby, Gkazinou, Beasley, and Macfarlane. Analysis and interpretation of data: McBeth, Prescott, Scotland, Lovell, McNamee, Symmons, and Macfarlane. Drafting of the manuscript: McBeth, Prescott, Scotland, and Woby. Critical revision of the manuscript for important intellectual content: McBeth, Prescott, Scotland, Lovell, Keeley, McNamee, Woby, Gkazinou, Beasley, Symmons, and Macfarlane. Statistical analysis: McBeth, Prescott, and Scotland. Obtained funding: McBeth, Prescott, Lovell, Keeley, McNamee, Symmons, Woby, and Macfarlane. Administrative, technical, and material support: McBeth, Keeley, Woby, Gkazinou, and Beasley. Study supervision: McBeth, Lovell, Keeley, McNamee, Symmons, Woby, and Macfarlane.
Financial Disclosure: None reported.
Funding/Support: This trial was supported by an award from Arthritis Research UK, Chesterfield, England, grant 17292.
Role of the Sponsors: The funder had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; or preparation, review or approval of the manuscript.
Additional Contributions: We are grateful to the following practices and their patients for participating in the study in Aberdeen: Carden Medical Centre, Elmbank Medical Practice, Great Western Medical Practice, Garthdee Medical Group, and Macclesfield: Readesmoor Medical Group Practice, Lawton House Surgery, Bollington Medical Centre, Park Lane Surgery. The Scottish Primary Care Research Network facilitated access to patient information at the practices in Aberdeen city. Charlie Stockton was the study manager during the setting up and for part of the conduct of the study. John Norrie (while director of CHaRT) and Ashraf El-Metwally, PhD (lecturer, Epidemiology Group), at the University of Aberdeen, were originally investigators for the MUSICIAN study. Alison MacDonald and Gladys McPherson of the Health Services Research Unit (HSRU) at the University of Aberdeen provided input regarding the conduct of the study. Dev Acharya, Jennifer Banister, Flora Joyce, and Michelle Rein from Aberdeen and Karen Kane and Rowan Jasper at the Arthritis Research UK Epidemiology Unit, University of Manchester, were the project assistants. Alison Littlewood, Arthritis Research UK Epidemiology Unit, University of Manchester, performed the study management at the Manchester site. Wesley Bramley, Richard Paxton, and Julie Carney delivered the exercise intervention. Matthew Cunningham, Central and Eastern Cheshire Primary Care Trust, Macclesfield District General Hospital, facilitated access to leisure facilities in Macclesfield. Marie Pope, Jayne Fox, Lindsay Rigby, and Nicola McConnell delivered the TCBT. Research nurses Daniel Barlow, Vivien Vaughan, and Roslyn Campbell conducted the prerandomization clinic assessments. We are grateful to the independent members of the Trial Steering Committee—Matthew Hotopf, MD, Tracey Howe, MD, and Martin Underwood, MD—and the Data Monitoring Committee—Marwan Bukhari, MD, Hazel Inskip, MD, and Chris Edwards, MD.