Accepted for Publication: September 5, 2011.
Author Contributions: Dr Peralta had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Peralta, Norris, Tamura, McCullough, and Shlipak. Acquisition of data: Li and Bakris. Analysis and interpretation of data: Peralta, Norris, Li, Chang, Jolly, McCullough, and Shlipak. Drafting of the manuscript: Peralta, Norris, Li, Bakris, and McCullough. Critical revision of the manuscript for important intellectual content: Peralta, Norris, Chang, Tamura, Jolly, McCullough, and Shlipak. Statistical analysis: Norris and Li. Obtained funding: Peralta. Administrative, technical, and material support: Norris, Tamura, McCullough, and Shlipak. Study supervision: Bakris and Shlipak.
KEEP Investigators: George Bakris, MD; Bryan Becker, MD; Andrew Bomback, MD; Wendy Brown, MD; Kerri Cavanaugh, MD; Shu-Cheng Chen, MS; Allan Collins, MD; Linda Fried, MD; Claudine Jurkovitz, MD; Mikhail Kosiborod, MD; Peter A. McCullough, MD; Samy McFarlane, MD; Rajnish Mehrotra, MD; Keith Norris, MD; Rulan Savita Parekh, MD; Carmen A. Peralta, MD; Nilka Rios Burrows, MPH; Georges Saab, MD; Stephen Seliger, MD; Michael Shlipak, MD; Lesley Stevens, MD; Lynda A. Szczech, MD; Manjula K. Tamura, MD; Joseph Vassalotti, MD; John Wang, MD, PhD; Adam Whaley-Connell, DO, MSPH.
Financial Disclosure: None reported.
Funding/Support: Dr Peralta is funded by National Institute of Diabetes and Digestive and Kidney Diseases grant 1K23SK082793 and a Robert Wood Johnson Harold Amos award. Dr Norris is supported by National Institutes of Health grants MD00148 and 1U54RR026138. KEEP is a program of the National Kidney Foundation and is supported by Amgen, Abbott, Novartis, Siemens, Genentech, Genzyme, Nephroceuticals, Pfizer, LifeScan, and Suplena.
Role of the Sponsor: The funding sources had no involvement in the design or execution of this study.
Additional Contributions: The other investigators, the staff, and the participants of the KEEP study provided valuable contributions.