Accepted for Publication: August 7, 2011.
Author Contributions: Dr Pham had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Pham, Chen, Sander, John-Baptiste, Thein, Wodchis, and Krahn. Acquisition of data: Pham, Stern, Thein, Gomes, Carcone, and Krahn. Analysis and interpretation of data: Pham, Chen, Sander, John-Baptiste, Thein, Gomes, Wodchis, Bayoumi, Machado, and Krahn. Drafting of the manuscript: Pham, Chen, Machado, and Krahn. Critical revision of the manuscript for important intellectual content: Pham, Stern, Sander, John-Baptiste, Thein, Gomes, Wodchis, Bayoumi, Carcone, and Krahn. Statistical analysis: Pham, Chen, John-Baptiste, Wodchis, Bayoumi, and Machado. Obtained funding: Pham and Krahn. Administrative, technical, and material support: Thein, Machado, Carcone, and Krahn. Study supervision: Krahn. Economic analysis of cost data: Sander. Validation of the model: John-Baptiste.
Published Online: September 26, 2011. doi:10.1001/archinternmed.2011.473
Financial Disclosure: None reported.
Funding/Support: Funding for this study was provided in part by the Ontario Ministry of Health and Long-Term Care to the Toronto Health Economics and Technology Assessment (THETA) Collaborative. The THETA Collaborative provides technology assessment support for the Ontario Health Technology Advisory Committee and the Medical Advisory Secretariat at Health Quality Ontario, an independent agency.
Role of the Sponsors: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.
Previous Presentations: This study was presented as a poster at the 2009 Symposium, Canadian Agency for Drugs and Technologies in Health; April 5-9, 2009; Ottawa, Ontario, Canada; and as an oral presentation at the 31st Annual Meeting of the Society for Medical Decision Making; October 19, 2009; Los Angeles, California.
Additional Contributions: Nancy Parslow, RN, ET, of the Toronto General Hospital, provided insightful comments and help during the preparation of the manuscript.